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RO5263397 can be a TAAR1 specific agonist with oral activity which has been Utilized in antidepressant research. It has also been identified to act as an inhibitor of the enzyme cyclooxygenase-2 (COX-two), which is involved with the synthesis of prostaglandins.Duchenne muscular dystrophy (DMD) is usually a fatal muscle disease a result of mutations
MOMIPP selectively impairs glycolytic metabolism in comparison with the non-cytotoxic analog, MOPIPP. a Sooner or later following plating, U251 cells had been handled with 10 μM MOMIPP or MOPIPP and examined by stage contrast microscopy once the indicated intervals. b & c 5 hrs after addition of ten μM MOMIPP or MOPIPP, U251 cells have been s